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Geometric mean atazanavir, ritonavir, and tenofovir plasma pharmacokinetic parametersa
| Drug | Value (geometric mean [95% CI])
|
|||
|---|---|---|---|---|
| AUC0-24 (ng·hr/ml) | Cmax (ng/ml) | C24 (ng/ml) | CL/F (liter/hr) | |
| Atazanavir | 35,971 (30,853-41,898) | 3,504 (2,978-4,105) | 578 (474-704) | 8.3 (7.2-9.7) |
| Ritonavir | 7,840 (6,292-9,769) | 842 (664-1,064) | 71 (53-102) | 12.8 (10.3-16) |
| Tenofovir | 2,762 (2,392-3,041) | 254 (221-292) | 60 (52-68) | 49.2 (43.8-55.3) |
Pharmacokinetics for 22 subjects were measured.
