Skip to main content
. 2007 Nov 12;52(2):612–618. doi: 10.1128/AAC.00836-07

FIG. 6.

FIG. 6.

Proposed mechanism of pyrophosphate-mediated target engagement by the lanthionine antibiotic subtilin. Membrane breach occurs in a lipid II-mediated fashion and cell wall synthesis is impeded through engagement of pyrophosphate-containing intermediates into complexes.