TABLE 1.
MICs of β-lactams for K. pneumoniae GR, its E. coli transconjugant TcGR, and an E. coli recipient strain
| β-Lactam(s)a | MIC (μg/ml)
|
||
|---|---|---|---|
| K. pneumoniae GR | E. coli J53 TcGR | E. coli J53 | |
| Amoxicillin | >256 | >256 | 4 |
| Amoxicillin + CLA | 48 | 24 | 4 |
| Ticarcillin | >256 | >256 | 2 |
| Ticarcillin + CLA | >256 | >256 | 2 |
| Piperacillin | >256 | 128 | 1 |
| Piperacillin + TZB | >256 | 128 | 1 |
| Cephalothin | >256 | >256 | 4 |
| Cefoxitin | 64 | 4 | 2 |
| Cefotaxime | >32 | 4 | 0.06 |
| Cefotaxime + CLA | 32 | 0.38 | 0.06 |
| Ceftazidime | >256 | 4 | 0.06 |
| Ceftazidime + CLA | 96 | 1 | 0.12 |
| Aztreonam | >256 | 16 | 0.03 |
| Aztreonam + CLA | >256 | 1.5 | 0.03 |
| Cefepime | >256 | 1.5 | 0.03 |
| Imipenem | 12 | 1.5 | 0.12 |
| Imipenem + CLA | 0.75 | 0.25 | 0.12 |
| Meropenem | 6 | 0.38 | 0.03 |
| Meropenem + CLA | 3 | 0.094 | 0.03 |
| Ertapenem | 12 | 0.38 | 0.03 |
| Ertapenem + CLA | 6 | 0.094 | 0.03 |
| Tigecycline | 3 | 0.5 | 0.5 |
| Gentamicin | 1.5 | 0.064 | 0.064 |
| Colistin | 128 | 0.38 | 0.38 |
a
CLA, clavulanic acid at a fixed concentration of 2 μg/ml; TZB, tazobactam at fixed concentration of 4 μg/ml.