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Binding the DT receptor. Competition for radiolabeled DT receptor binding. Cold competitor proteins, native DT (▵), Bcl-xL–DTR (▴), Bcl-xL (○), and DTR (●) were used to displace I125-labeled DT tracer. Native DT and Bcl-xL–DTR compete for DT receptor binding in the nanomolar concentration range.
