Table 1.

Mutation frequency of LN12 cells expressing Y265C and β-WT proteins

Dex	cII mutation frequency × 10−4 ± SE
	Y265C	β-WT	Y265C/β-WT
+	8.6  ±  2.5	1.0  ±  0.4	8.6
−	2.0  ±  0.4	2.0  ±  0.81	1

Experiments were performed three times. At least 100,000 plaques were scored for Y265C and β-WT in the absence of Dex induction. For Y265C, 746,000 plaques were scored after induction with Dex. For β-WT, 281,000 plaques were scored after induction with Dex. The baseline-mutation frequency for LN12 cells in the absence of either Y265C or β-WT expression systems is 2.4 ± 0.3 × 10⁻⁴.