Amino-acid sequence alignment of α-11 giardin (alpha11) and annexins A1, A2, A4, A5, A6 and A7. Residues denoted as white letters on a red background are strictly conserved. Residues denoted in red on a cyan background are homologous, while residues denoted in black on a cyan background are non-homologous in this group. The alignment was performed using the program ClustalW (Thompson et al., 1994 ▶) and the figure was prepared using ESPript (Gouet et al., 1999 ▶).