Table 1.

PZ lines that suppress or enhance wg-induced leg-to-wing transdetermination

Genotype	LacZ expression	In situ expression	Frequency (%) of Vg expression in leg discs (n = discs)	Frequency (%) of legs with wing tissue (n = discs)
Act>wg			32 (60)	25 (69)
Suppressors
l(3)01629	Class 4	N/A	4 (113)*	11(19)
taiman (tai01351)	Class 4	N/A	5 (97)*	8 (24)
Secβ6107214	Class 3	Class 3	6 (107)*	6 (46)**
polo01673	Class 4	N/A	7 (53)**	15 (34)
Krüppel-homolog-1 (Kr-h110642)	Class 3	Class 4#	8 (128)*	10 (30)
Syx1301470	Class 3	N/A	8 (97)*	6 (31)**
ken and barbie (ken02970)	Class 1	Class 1	9 (114)*	3 (40)**
oho23B03575	Class 2	Class 2	9 (88)*	13 (23)
cyclin A (cycA03946)	Class 1	Class 1	10 (119)*	19 (54)
l(2)00248	Class 3	N/A	10 (96)*	12 (30)
CG309471483a	Class 1	Class 1	10 (80)**	15 (20)
l(3)05203	Class 4	N/A	11 (74)**	23 (40)
rpd304556	Class 3	Class 3/4	12 (122)**	35 (20)
jing01094	Class 4	Class 4	13 (113)**	3 (32)**
combgap (cg07659)	Class 4	Class 4	13 (100)**	10 (20)
Nup15401501	Class 3	Class 3	13 (68)**	8 (26)
Aly02267	Class 4	Class 4	15 (117)**	5 (40)**
Enhancers
l(3)01344	Class 4	Class 2#	59 (92)**	25 (24)
S6 kinase (S6k07084)	Class 3	Class 3/4	48 (82)**	19 (48)

Data shown are from prothoracic leg discs and adult legs. 90 PZ insertion lines (see Supplementary Table 1) were examined for their ability when heterozygous mutant to dominantly modify wg-induced regeneration and transdetermination. Transdetermination frequency in leg discs and adult cuticle were generated from animals heat shocked at 60 h AED (37 °C) to induce ubiquitous wg expression.

^*Asterisk(s) indicate p-values <0.001;

^**indicate p-values within 0.01–0.05. The lacZ and in situ expression patterns of each PZ insertion falls into 4 different classes after ubiquitous wg expression (see Fig. 2, for details). The number sign (#) indicates that the lacZ expression pattern differed significantly from the in situ expression pattern (Fig. 5). N/A, in situ expression is not available.