Skip to main content
. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Mech Dev. 2007 Oct 12;125(1-2):67–80. doi: 10.1016/j.mod.2007.10.003

Table 3.

Summary of genes that function in leg disc regeneration

Gene Expression during regeneration Blastema formation wg-induced transdeterminations
Leg-to-wing Eye-to-wing Antenna-to-wing Maxillary palp-to-wing Genital-to-wing
Kr-h1^ Blastema-specific NC S S S S NC
rpd3 Ubiquitous/blastema Reduced S S S NC NC
jing^ Blastema-specific Reduced S S S S S
cg^ Blastema-specific Delayed S S S S S
Aly Blastema-specific Delayed S S S NC NC
S6k Ubiquitous/blastema NC E NC S NC NC

Six genes were identified that met both criteria of our screen, that is, they displayed expression in the regeneration blastema during leg disc regeneration and significantly modified regeneration-induced leg-to-wing transdetermination. Expression patterns are based on whole-mount in situ hybridization in the leg disc. S, suppresses; E, enhances; NC, no significant change.

^

Indicates that more than one allele was tested and found to modify wg-induced leg-to-wing transdetermination. All of the genes when heterozygous mutant dominantly modify at least one other (besides leg-to-wing) wg-induced transdetermination event.