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. 2008 Feb;9(2):93–99. doi: 10.1631/jzus.B0710599

Table 3.

Association between maternal MTRR genotype and Down syndrome-affected pregnancies (case mothers) (n=64) and control mothers (n=70)

Genotype Number (percentage) of case mothers Number (percentage) of control mothers Odds ratio 95% CI P
AA 10 (15.6%) 24 (34.3%) 1.00
AG 28 (43.8%) 34 (48.6%) 1.98 2.25~4.82 >0.05
GG 26 (40.6%) 12 (17.1%) 5.20 1.90~14.22 <0.025
AG or GG 54 (84.4%) 46 (65.7%) 2.81 1.06~7.39 >0.1