Table 2.

Review of cases of primary leiomyosarcomas of the nipple-areola region

Reference*	Site	Age/sex	Size (cm)	Mitoses	Treatment	Follow-up
Crocker and Murad, 1969	Right, above the nipple	51/male	5	Common	Radical mastectomy	–
Pardo-Mindan et al., 1974	Left, near the nipple	49/female	7	16/10 HPF	Simple mastectomy	Alive at 6 months, NET
Hemandez, 1978	Left, involving nipple	53/male	4	15/10 HPF	Modified radical mastectomy	Alive at 1 year and 2 months, NET
Yatsuka et al., 1984	Left, beneath the nipple	56/female	1.5	21/10 HPF	Radical mastectomy	Alive at 4 years and 7 months, NET
Nielsen, 1984	Right, edge of the areola	24/female	1.5 (1962) r	2/10 HPF	Excision in 1960, 1962	Died 20 years later with metastases to brain, skin, thyroid gland, and kidneys
			1 (1965) r	8/10 HPF	Excision
			2 (1966) r	14/10 HPF	Excision and simple mastectomy
Lonsdale et al., 1992	Left, areola	60/female	2	10/10 HPF	Excision with 1 cm safe margin	Alive at 3 months, post-mastectomy, NET
			4.5 (18 months later) r		Excision with subsequent mastectomy
Uğraş et al., 1995	Right, under areola	47/female	2	3/10 HPF	Total excision and subcutaneous simple mastectomy	Alive at 1 year and 6 months, NET
The present case described in this article	Left, involving nipple-areola complex	52/female	1.5	7/10 HPF	Excision (July, 2007) and subsequent total mastectomy and regional lymph node dissection	Alive

^*All the references are from Uğraş et al.(1997)

NET: No evidence of tumor; r: Recurrence