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. Author manuscript; available in PMC: 2008 Feb 15.
Published in final edited form as: Int J Cancer. 2008 Feb 15;122(4):742–750. doi: 10.1002/ijc.23114

Figure 5.

Figure 5

Cannabinoid receptor immunoreactivity of nerves in pancreatic cancer. Low (a, g), moderate (b, h) and strong (c, i) immunostaining for CB1 or CB2 receptors, respectively, in nerves of pancreatic cancer tissues. (d–f and j–l) Corresponding specificity controls pre-adsorbed with the respective blocking peptide. (m) High CB1 levels in pancreatic nerves are associated with a lower pain score (p = 0.012), while no such association is seen for CB2 levels (p = 0.35). (n) Kaplan–Meier survival curves of patients with low and high pain scores. Median survival was 11 months for patients with low pain scores and 24.5 months for patients with high pain scores (p = 0.0343).