Table 3.
Change in Posttreatment Prostaglandin Levels in Rectal Mucosa of Patients Taking Sulindac Who Remained Polyp Free Compared With Patients on Sulindac Who Developed Polyps
| Mean percentage of baseline value (± SD)
|
|||
|---|---|---|---|
| Prostaglandin | Polyp-free group (n =11) | Group with polyps (n =10) | P valuea |
| PGD2 | 58.4 ± 21.0 | 86.6 ± 81.2 | 0.023 |
| PGE2 | 66.1 ± 23.1 | 102.4 ± 72.5 | 0.117 |
| PGF2α | 76.5 ± 29.3 | 115.2 ± 65.5 | 0.082 |
| TXB2 | 63.5 ± 28.0 | 138.1 ± 112.3 | 0.038 |
| 6KF1α | 70.2 ± 30.2 | 170.7 ± 150.5 | 0.035 |
a
Calculated by t test.