Table 5.
Change in Posttreatment ODC Activities and Polyamine Levels in Rectal Mucosa of the Sulindac Group Compared With the Placebo Group
Mean percentage of baseline value (± SD)
|
|||
---|---|---|---|
Parameter | Sulindac group (n =21) | Placebo group (n =20) | P valuea |
ODC activityb | 127 ± 0.09 | 214 ± 1.71 | 0.15 |
Putrescinec | 133 ± 0.62 | 121 ± 0.74 | 0.67 |
Spermidine | 124 ± 0.51 | 127 ± 0.48 | 0.85 |
Spermine | 112 ± 0.44 | 129 ± 0.49 | 0.36 |
Calculated by t test.
ODC activities are expressed as pmol CO2 per mg soluble protein per hour.
Polyamine contents are expressed in nmol of polyamine per mg soluble protein.