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Ribozyme target sequences and siRNA related sequences in βS-globin mRNA and related sequences in γ-globin mRNA. Underlined: ribozyme target sequence; X and x: base(s) that differ between β-globin and βS-globin mRNA and corresponding γ-globin mRNA. X was the mismatch near the cleavage site of ribozyme or in the middle region of the siRNA. Note the difference between β- and βS-globin mRNA is showed in zb2. The number is according to β-globin mRNA or cDNA.
