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. 1999 Jun 1;113(6):837–849. doi: 10.1085/jgp.113.6.837

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Comparison of single channel currents in the presence of 0.2 μM InsP₃ and 0.1 μM free Ca. A represents an experimentally measured channel recording, whereas B represents a simulation, generated from the current mathematical model. C shows a dwell-time histogram obtained from 5 min of the simulated trace from which a representative stretch is shown in B. The open time distribution is accurately fit by a biexponential curve using the same parameters as for the experimental data shown in Fig. 5 B.