Table 1.
Group | Dilution | Uninfected/Total | G.M. Oocyst | Percent Oocyst Reduction | % Infected |
---|---|---|---|---|---|
EP | 1:2 | 21/23 | 1.0a,b | 97.5 | 8.5 |
EP | 1:4 | 8/28 | 3.4a,b | 91.0 | 71.4 |
EP | 1:8 | 1/23 | 9.5 | 76.0 | 95.6 |
EP | 1:16 | 0/30 | 51.9 | 0 | 100 |
No EP | 1:2 | 10/26 | 3.6a | 91.0 | 61.5 |
No EP | 1:4 | 3/25 | 38.8 | 1.0 | 88 |
No EP | 1:8 | 1/26 | 55.3 | 0 | 96 |
No EP | 1:16 | 7/22 | 89.9 | 0 | 68 |
Pre- immune | 1:2 | 4/22 | 28.9 | 81 | |
Pre- immune | 1:4 | 3/26 | 49.7 | 85 |
Column “Uninfected/Total” shows the number of uninfected mosquitoes over total number mosquitoes in that group, and column “% Infected” shows the percentage total infected mosquitoes per group at a given dilution. Column “GM Oocyst” indicates the geometric mean [GM] oocyst burden per mosquitoe for that group and column “Percent Oocyst Reduction” shows the percentage oocyst reduction for that group compared to the average GM oocyst burden of the two pre-immunization control feeds. Statistical significance was assessed by Mann-Whitney t-test. Statistical significance for oocyst count differences when compared between immune and pre-immune sera are represented by ‘a’ (p<0.05) and those between sera from mice immunized with or without EP are represented by ‘b’ (p<0.0.025).