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Example of a Positive 12-Day IVS Assay for Peptide Recognition
| # of Vaccinations
|
|||
|---|---|---|---|
| Stimulus | 0 | 2 | 4 |
| pg/ml IFN-γ | |||
| T2/ESO-1 (N) | 380 | 2896 | 2723 |
| T2/ESO-1 (9V) | 309 | 2994 | 2554 |
| T2/gp 100:180-188 | 234 | 45 | 22 |
| Unpulsed T2 | 282 | 57 | 20 |
| 624mel (A2+, ESO-1+) | 105 | 21 | 10 |
| 1363mel (A2+, ESO-1+) | 83 | 62 | 20 |
| 624.28mel (A2−, ESO-1+) | 41 | 15 | 1 |
| 526mel (A2+, ESO-1−) | 29 | 5 | 0 |
| None | 124 | 27 | 15 |
ESO-1(N), native NY-ESO-1:157-165 peptide; ESO-1(9V), modified peptide NY-ESO-1:157-165(9V); gp100:180-188, irrelevant peptide.
