Table 2. .
Analysis of Candidate Genes at the 1p34-36 MI Locus for Association with CAD and MI[Note]
|
P |
||||
| Gene | Positiona (Mb) |
SNP | CADb | MIc |
| MFAP2 | 17.1 | rs2235932 | .552 | .632 |
| PLA2G2A | 20.1 | rs4744 | .202 | .476 |
| HMGCL | 23.9 | rs719400 | .375 | .338 |
| LDLRAP1 | 25.6 | rs11563 | .686 | .246 |
| NR0B2 | 26.9 | rs7504 | .131 | .288 |
| SLC9A1 | 27.2 | rs11247613 | .683 | .852 |
| AK2 | 33.1 | rs998664 | .197 | .300 |
| GJB5 | 34.9 | rs2275229 | .730 | .700 |
| CSF3R | 36.6 | rs3917924 | .630 | .500 |
| CDC20 | 43.5 | rs839763 | .815 | .744 |
| FAAH | 46.6 | rs324420 | .916 | .736 |
| LRP8 | 53.5 | rs5174 | .003 | .004 |
Note.— The entire 1p34-36 locus spans a region from 4.0 Mb (CATC015) to 59.1 Mb (GATA26G09P), with the plateau of genomewide significance from 13.2 Mb (GATA27E01) to 34.1 Mb (ATA79C10) (information on the markers can be found at Marshfield Genotyping Service).
a
Positions as shown in the UCSC Genome Browser.
b
P value for association with CAD.
c
P value for association with MI.