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Sib-TDT Analysis in the GeneQuest and GeneQuest II Populations
| Population | Risk Allelea | Minor Allelesb | Z Score | P |
| GeneQuest | A | 170 | 2.63 | .005 |
| GeneQuest II | A | 72 | 2.34 | .009 |
Allele A at the nucleotide level corresponds to variant 952Q at the protein level.
The number of minor alleles among affected sibs across all sibships.
