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. Author manuscript; available in PMC: 2008 Feb 4.
Published in final edited form as: Antioxid Redox Signal. 2005;7(11-12):1568–1580. doi: 10.1089/ars.2005.7.1568

FIG. 5. Reversal of diabetes-induced endothelial dysfunction by pharmacological inhibition of PARP in diabetic NOD mouse vascular rings.

FIG. 5

Epinephrine-induced contractions (upper panel), acetylcholine-induced endothelium-dependent relaxation (middle panel), and sodium nitroprusside (SNP)-induced endothelium-independent relaxations (lower panel).■, control; ○, control + PJ34; □, diabetes; ●, diabetes + PJ34. Each point of the curve represents the mean ± SE of five to eight experiments in vascular rings. *p < 0.05 versus control; #p < 0.05 versus diabetes. Reproduced with permission from 72.