Table 1.

In vivo T cell depletion delays Borna disease in mice

Experiment	Administration of mAb* (days p.i.)	No. of fatally diseased mice (score 2)†/no. of treated mice
		Not depleted	CD4-depleted	CD8-depleted
1	15 and 18	4/4	0/3	0/3
2	18 and 22	2/2	1/3	2/3
3	15 and 18	3/3	0/3	0/3

^*MRL mice infected as newborns with a BDV stock passaged four times in newborn rats were injected i.p. with 170–200 μl of a 100-fold concentrated hybridoma supernatant containing either anti-CD4 (YTS 191.1) or anti-CD8 (YTS 169.4.2) mAb (27). p.i., postinfection. 

^†Numbers refer to development of disease within 7 weeks after infection.