Table 2.
Univariate analysis(a) and multivariate logistic regression analysis(b) of variables predicting risk for late acute rejection
| (a) | |||||
|---|---|---|---|---|---|
| Variables | Rejection N (%) | No rejection N (%) | OR* | 95%C.I.* | P |
| Recipient gender (M:F) | 20 : 7 | 93 : 47 | 0.437 | ||
| Recipient age (years) | 33.0 ± 12.4 | 36.5 ± 10.6 | < 0.0001 | ||
| Donor age (years) | 42.0 ± 12.3 | 39.6 ± 14.4 | < 0.0001 | ||
| Number of HLA-mismatch | 2.96 ± 1.02 | 2.80 ± 1.37 | < 0.0001 | ||
| Donor serum creatinine (mg dL−1) | 0.96 ± 0.15 | 0.99 ± 0.48 | < 0.001 | ||
| Cadaveric donors | 4 (14.8%) | 21 (15.1%) | 0.98 | 0.32–3.26 | 0.969 |
| Calcineurin inhibitors | 25 (92.6%) | 124 (89.2%) | 1.51 | 0.33–7.03 | 0.598 |
| Anti IL-2 receptor antibody | 4 (14.8%) | 34 (24.3%) | 0.54 | 0.18–1.68 | 0.288 |
| GG at MCP-1-2518 | 14 (52.9%) | 41 (29.3%) | 2.60 | 1.13–6.01 | 0.025 |
| (b) | |||
|---|---|---|---|
| Variables | ORa | 95% C.I.b | P |
| Recipient age (years) | 0.99 | 0.95–1.03 | 0.565 |
| Donor age (years) | 1.02 | 0.98–1.05 | 0.382 |
| Number of HLA-mismatch | 1.06 | 0.77–1.47 | 0.714 |
| Donor serum creatinine (mg dL−1) | 0.90 | 0.27–3.02 | 0.858 |
| GG at MCP-1-2518 | 2.63 | 1.05–6.58 | 0.043 |
*
OR; odds ratio
*
C.I.; confidence interval.
a
OR; odds ratio
b
C.I.*; confidence interval.