Table 5.
Cox proportional hazard model to test the significance of clinical covariates and genotypes of MCP-1 polymorphism as predictors of graft failure with acute rejection episodes
Variable | ORa | 95% C.I.b | P-value |
---|---|---|---|
Donor age (years) | 1.02 | 1.000–1.045 | 0.056 |
Recipient age (years) | 1.01 | 0.983–1.039 | 0.449 |
HLA-DR mismatch | 2.46 | 1.165–5.206 | 0.019 |
Donor serum creatinine (mg dL−1) | 2.25 | 1.022–4.493 | 0.045 |
GG genotype at MCP-1-2518 | 2.27 | 1.189–4.346 | 0.014 |
OR; odds ratio
C.I.; confidence interval.