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. 1985 Sep 1;86(3):395–411. doi: 10.1085/jgp.86.3.395

Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis

PMCID: PMC2228802  PMID: 2997364

Abstract

Large changes in the opacity of the unstained mouse neurohypophysis follow membrane potential changes known to trigger the release of peptide hormones. These intrinsic optical signals, arising in neurosecretory terminals, reflect variations in light scattering and depend upon both the frequency of stimulation and [Ca2+]o. Their magnitude is decreased in the presence of Ca2+ antagonists and by the replacement of H2O in the medium by D2O. These observations suggest a correspondence between the intrinsic optical changes and secretory activity in these nerve terminals.

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Selected References

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