Table 2.
RHD alleles predicted from coding sequence polymorphism
| Allele | Nucleotide aberrations | Amino acid aberrations | Donors carrying the allele | Reference |
| RHD | None (reference sequence) | None | 42 | [20] |
| DAU-0 | 1136C > T | T379M | 18 | [9] |
| RHDΨ | RHDΨ † | M218I, F223V, S225F, Y269X | 7 | [5] |
| Ccdes ‡ | 186G > T, 410C > T, 455A > C | L62F, A137V, N152T | 5 | [6] |
| DAU-0.1 | 579G > A, 1136C > T | T379M | 2 | This work |
| RHD(384T > C) | 384T > C | None | 1 | This work |
| DMA/ | 621G > C | L207F | 1 | This work |
| DAU-3 | 835G > A, 1136C > T | V279M, T379M | 1 | [9] |
* The sum is less than 116 alleles, because homozygous occurrences were not accounted for. † All RHDΨ alleles detected carried the 37 bp duplication at the intron3/exon 4 junction and the five single nucleotide substitutions 609G > A, 654G > C,667T > G,674C > T, and 807T > G as previously described by Singleton et al. [5]. ‡ In three donors, the observed aberrations would also be compatible with the presence of the DIII type 4 allele, because normal RHD sequences occurred in trans.