Table II.
Permeability of Wild-Type Channels to Intracellular Anions
| Intracellular anion | Erev | PX/PCl | n | |||
|---|---|---|---|---|---|---|
| mV | ||||||
| Chloride | 0 | 1.00 | 8 | |||
| Iodide | +15.5 ± 1.4 | 1.82 ± 0.10 | 6 | |||
| Bromide | +5.8 ± 3.5 | 1.26 ± 0.17 | 4 | |||
| Fluoride | −46.7 ± 11.7 | 0.17 ± 0.07 | 5 | |||
| Nitrate | +11.3 ± 1.4 | 1.61 ± 0.09 | 6 | |||
| Formate | −35.4 ± 0.0 | 0.25 ± 0.00 | 4 | |||
| Bicarbonate | −34.5 ± 1.5 | 0.25 ± 0.01 | 3 | |||
| Acetate | −41.5 ± 0.4 | 0.19 ± 0.01 | 3 | |||
| Propanoate | No reversal | <0.06 | 2 | |||
| Pyruvate | No reversal | <0.06 | 4 | |||
| Methane sulfonate | No reversal | <0.06 | 3 | |||
| Ethane sulfate | No reversal | <0.06 | 5 | |||
| Gluconate | No reversal | <0.06 | 6 |
Summary of mean reversal potentials and permeability ratios measured with different intracellular anions in wild-type channels. See Table I for details.