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. 1997 Oct 1;110(4):415–440. doi: 10.1085/jgp.110.4.415

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Effects of couplon length. (A) Variation of the peak/steady release ratio as a function of couplon length. (B) Peak release current and (C) peak/steady ratio as a function of pulse voltage at four couplon lengths. Current is scaled up, in all cases, to a 60-channel couplon. The simulations illustrate one of the effects of conditioning pulses, which is to reduce the length of excitable patches. This in turn shifts the voltage dependence of peak release and moves the maximum peak/steady ratio to higher voltages.