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. 1997 Oct 1;110(4):415–440. doi: 10.1085/jgp.110.4.415

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Steady state Ca²⁺ microdomains created by 1-pA release at each of 15 release channel sites along one row of the couplon. The stacked pairs of plots represent the calcium profiles along the length of the couplon, when the (constant) calcium source is located at different channel positions. In each pair, the larger values are concentrations along the line of centers of the releasing channels, and the lower values correspond to the line of centers of the channels on the other row. These numbers were rescaled by the actual unitary currents (0.1 for V channels, 0.3 for C channels) to give the local [Ca²⁺] coupling coefficients used in the simulations.Figure 9. Steady state Ca²⁺ microdomains created by 1-pA release at each of 15 release channel sites along one row of the couplon. The stacked pairs of plots represent the calcium profiles along the length of the couplon, when the (constant) calcium source is located at different channel positions. In each pair, the larger values are concentrations along the line of centers of the releasing channels, and the lower values correspond to the line of centers of the channels on the other row. These numbers were rescaled by the actual unitary currents (0.1 for V channels, 0.3 for C channels) to give the local [Ca²⁺] coupling coefficients used in the simulations.

Steady state Ca²⁺ microdomains created by 1-pA release at each of 15 release channel sites along one row of the couplon. The stacked pairs of plots represent the calcium profiles along the length of the couplon, when the (constant) calcium source is located at different channel positions. In each pair, the larger values are concentrations along the line of centers of the releasing channels, and the lower values correspond to the line of centers of the channels on the other row. These numbers were rescaled by the actual unitary currents (0.1 for V channels, 0.3 for C channels) to give the local [Ca²⁺] coupling coefficients used in the simulations.Figure 9. Steady state Ca²⁺ microdomains created by 1-pA release at each of 15 release channel sites along one row of the couplon. The stacked pairs of plots represent the calcium profiles along the length of the couplon, when the (constant) calcium source is located at different channel positions. In each pair, the larger values are concentrations along the line of centers of the releasing channels, and the lower values correspond to the line of centers of the channels on the other row. These numbers were rescaled by the actual unitary currents (0.1 for V channels, 0.3 for C channels) to give the local [Ca²⁺] coupling coefficients used in the simulations.