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. 1997 Oct 1;110(4):453–465. doi: 10.1085/jgp.110.4.453

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The pH_i recovery from an acid load in the nominal absence of CO₂/HCO₃ ⁻ is sensitive to EIPA. (A) Effect of EIPA on the pH_i recovery from an acid load. An astrocyte was acid loaded by applying and withdrawing 20 mM NH₃/NH₄ ⁺ (a–d). EIPA (10 μM) was present during the pH_i recovery (de). (B) The pH_i dependence of acid extrusion in the absence (circles) and presence (open squares) of 10 μM EIPA. (inset) The pH_i dependence of the EIPA-sensitive component of acid extrusion (closed squares). These data were obtained by subtracting the open squares in the main panel from the open circles.