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. 1998 Jul 1;112(1):55–69. doi: 10.1085/jgp.112.1.55

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Representative traces from a single channel at holding potentials of +60 and −60 mV in the presence of 500 nM 21-amino-9α-hydroxy-ryanodine in the solution at the luminal face of the channel (left) or in the presence of 500 nM 21-amino-9α-hydroxy-ryanodine in both luminal and cytosolic solutions (right). C, closed; M, modified; O, open.