Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1998 Jul 1;112(1):55–69. doi: 10.1085/jgp.112.1.55

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Variation in P _mod with increasing P _o. The figure shows current fluctuations of a single sheep cardiac RyR channel at a holding potential of +40 mV with 700 nM 21-amino-9α-hydroxy- ryanodine in the solution at the cytosolic face of the channel. Channel P _o was increased by the addition of EMD 41000 to the solution at the cytosolic face of the channel (see text for details). Note the excess noise of the modified conductance state decreases as channel P _o increases. C, closed; M, modified; O, open.