Table II.
Channel Open and Closed Times
| Channel type | Open time | Closed time | n | |||
|---|---|---|---|---|---|---|
| αβ (+ 1.0 μM amil) | 32 ± 2 ms | 23 ± 1 ms | 4 | |||
| αβT (+ 1.0 μM amil) | 26 ± 1 ms | 26 ± 3 ms | 3 | |||
| αγ high P o | 6.9 ± 1.3 s | 1.9 ± 0.9 s | 3 | |||
| αγ low P o | 0.7 ± 0.3 s | 4.7 ± 1.1 s | 3 | |||
| αγT | 1.2 ± 0.1 s | 400 ± 20 ms | 3 | |||
| αγT + 0.1 μM amil | 151 ± 1 ms | 365 ± 9 ms | 3 |
Summary of mean open and closed times for the channel types. Values were calculated using the Pstat program within pClamp 6. In all cases, only one exponential could be fitted to the open or closed time histograms. The number of single channel patches used to generate the values are indicated in the far right column.