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. 1998 Nov 1;112(5):549–558. doi: 10.1085/jgp.112.5.549

Figure 8.

Figure 8

Kinetic parameters of 86Rb influx through the Na-K-Cl cotransporter based on the ordered binding model of Lytle et al. (1998) and Miyamoto et al. (1986). Plotted are predicted values of observed 1/K m for Na (left), Rb (center), or Cl (right) as a function of change of Na or Rb affinities (top), of Cl affinities at two sites (center), or of the rate constants for translocation of loaded or unloaded carriers (bottom). Values of the model parameters are given in methods; predicted K m values are relative to 14.2, 1.5, and 32 mM for Na, Rb, and 2Cl, respectively.