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. 1999 Oct 1;114(4):561–574. doi: 10.1085/jgp.114.4.561

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© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Effect of okadaic acid on insulin-stimulated pump current. (A) Representative tracing comparing pump current responses of insulin (850 nM)-treated monolayers before and after pretreatment with okadaic acid (100 nM). (B) Histogram illustrating the effect of okadaic acid on insulin activation of K⁺-stimulated pump current (n = 6, N = 4) compared with insulin (n = 7, N = 4) and a serum-free control group (n = 12, N = 5).