Figure 1.
Voltage-dependent gating of KcsA. A membrane containing at least five KcsA channels was held at 175 mV, with 100K7//100K4 solutions (cis//trans). Voltage was reversed in polarity where indicated. The current record was blanked during amplifier saturation after the voltage change and was subsequently corrected by fitting blank capacitative transients. Dashed lines represent closed-state level in all figures.