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. 2000 Aug 1;116(2):101–124. doi: 10.1085/jgp.116.2.101

Figure 15.

Figure 15

In this version of the model the reference state was modified by eliminating convective flows across tight junction so that S and paracellular markers pass this membrane by diffusion, only. Note that the flux of the driving solute is here directed from lateral space to outer compartment, i.e., also across the outer border of the epithelium is there recirculation of the driving solute. Reference-state values (Table ) except for the following variables: PStm = 1.5·10−12 cm·s−1, PStm,diff = 1.5·10−6 cm·s−1, PTtm = 2.25·10−12 cm·s−1, PTtm,diff = 2.25· 10−6 cm·s−1, L tm = 7.5·10−13 (cm· s−1)·(N·cm−2)−1, L a = 5·10−7 (cm·s−1)·(N·cm−2)−1, L s = 5· 10−7 (cm·s−1)·(N·cm−2)−1, L lm = 2·10−6 (cm·s−1)·(N·cm−2)−1.