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. 2001 Sep 1;118(3):291–302. doi: 10.1085/jgp.118.3.291

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Modification of R850C and R853C sodium channels by MTSEA and MTSET. Conductance-voltage relationships for R850C (A) and R853C (B) in control and after modification by MTSEA or MTSET. The data were fit with a Boltzmann relationship with V_1/2 = −24.1 ± 0.1 mV, k = 6.8 mV for R850C (n = 11); V_1/2 = −30.5 ± 0.3 mV, k = 7.8 mV for R850C-MTSEA (n = 9); V_1/2 = −39.9 ± 0.5 mV, k = 6.3 mV for R850C-MTSET (n = 18); V_1/2 = −31.7 ± 0.2 mV, k = 7.1 mV for R853C (n = 12); V_1/2 = −16.1 ± 0.3 mV, k = 7.7 mV, for R853C-MTSEA (n = 11); and V_1/2 = −29.6 ± 0.2 mV, k = 7.4 mV for R853C-MTSET (n = 9).