Table 1.

Voltage Dependence of Na_v1.2a and Mutants

	Activation			Inactivation
	Control V1/2	Slope	n	Control V1/2	Slope	n
	mV	mV		mV	mV
Nav1.2a	−36.7 ± 0.6	5.8 ± 0.5	4	−68.3 ± 1.0	−10.2 ± 0.8	4
R850Q	−27.5 ± 0.2	6.6 ± 0.2	4	−68.8 ± 1.3	−9.7 ± 0.6	4
R850C	−24.1 ± 0.1	6.8 ± 0.1	11	−69.3 ± 0.4	−8.1 ± 0.3	10
R853Q	−33.7 ± 0.3	7.1 ± 0.3	5	−70.9 ± 0.6	−7.1 ± 0.4	4
R853C	−31.7 ± 0.2	7.1 ± 0.1	12	−69.3 ± 0.8	−7.5 ± 0.7	7
R856Q	−25.7 ± 0.3	8.5 ± 0.2	5	−66.1 ± 0.2	−6.0 ± 0.2	2
K859Q	−20.8 ± 0.2	7.2 ± 0.2	3	−64.0 ± 0.4	−7.4 ± 0.4	3
K862Q	−27.6 ± 0.2	5.1 ± 0.2	3	−59.9 ± 0.6	−9.9 ± 0.5	4