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. 2002 Sep;120(3):323–335. doi: 10.1085/jgp.20028614

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Copyright © 2002, The Rockefeller University Press

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Figure 1. — Na⁺ block of KcsA: structure and function. (A) Structure of KcsA pore showing selectivity filter occupied by K⁺ (black circles) and cytoplasmic vestibule containing Na⁺ (gray circle). (B) Continuous single-channel recording of KcsA in 100 mM K⁺ before and after addition of 10 mM internal Na⁺. These 4-s traces were filtered at 1 kHz.