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. 2002 Sep;120(3):437–446. doi: 10.1085/jgp.20028621

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Copyright © 2002, The Rockefeller University Press

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Figure 4. — Initial open probability in zero ATP (P_o,zero) obtained from noise analysis (NA method, mean ± SEM, n = 3–8) plotted versus P_o,zero obtained from subsequent increase in current following PIP₂ addition (PIP₂ method, mean ± SEM). The solid line is a least squares fit to the mean data as indicated. The insert shows mean P_o,zero (PIP₂ method) plotted against I_initial (from Fig. 1 B) for each mutant.