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. 2002 Oct;120(4):497–508. doi: 10.1085/jgp.20028573

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Copyright © 2002, The Rockefeller University Press

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Figure 7. — Extracellular protons influence the inhibition by sodium more than the inhibition by tetrapropylammonium. Ouabain-sensitive ⁸⁶Rb influx was determined as described in materials and methods in DIDS-treated red blood cells. Shown are the mean and standard deviation of a representative experiment of a total of three that were done under these conditions. In this experiment, the slope in the absence of inhibitor (circle) was 0.447 ± 0.055, in the presence of 0.5 mM tetrapropylammonium (triangle) was 0.149 ± 0.032, and in the presence of 22.5 mM sodium (square) was 0.212 ± 0.006. The slope of flux versus proton concentration was statistically significantly different for tetrapropylammonium and for sodium in all three experiments.