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. 2002 Oct;120(4):567–579. doi: 10.1085/jgp.20028665

Figure 5.

Figure 5.

The effect of low pHi on the response of VCa to the application of 10 mM caffeine. The first half of a long experiment is shown, including the period during which the calcium-sensitive microelectrode was pushed right through the cell and then withdrawn back into the cell. After two applications of 10 mM caffeine, an HCl microelectrode was inserted through which currents were passed to decrease pHi, shown as downward deflections on the current record. Caffeine was applied as shown by the bars below the VCa record, and bicarbonate (5 mM) was applied for two periods as indicated.