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. 2003 Aug;122(2):225–237. doi: 10.1085/jgp.200308822

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Copyright © 2003, The Rockefeller University Press

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Figure 7. — Disulfide bond formation that promotes channel opening in the E229C/R314C mutant does not involve endogenous cysteines. Representative recordings of WT and E229C channels showing the lack of time-dependent current increase in K-INT/EDTA and the lack of response to DTT.