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. 2002 Nov;120(5):739–755. doi: 10.1085/jgp.20028639

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Copyright © 2002, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Figure 9. — Sensitivity of current magnitude in different channels to changes in external [K⁺]. (A–B) Data were derived from experiments in Fig. 8, where the percentage change in current was measured by comparing the current magnitude in trace 2 (dashed lines) to that in trace 1. Data for Kv2.1 in A and B are identical and were duplicated for ease of comparison to other channels. Straight lines are linear regression fits to the data. Each data point represents 3–9 cells tested. (C, top) Currents recorded from channels indicated at a membrane potential of −20 mV. Solid line is current recorded in 0 mM external K⁺. The dashed line illustrates current recorded when external [K⁺] was switched from 0 to 10 mM 100 ms after the start of the depolarization. Calibration bars, 0.5 nA for wild-type Kv2.1; 1 nA for all other channels. (C, bottom) Data were collected and linear regression fits obtained for all channels as in A and B. The slope of the regression is plotted on the ordinate.