Table 1.
Characteristics of study population according to genotype
| Characteristics | Genotype 2 (n = 72) | Genotype 3 (n = 108) | Genotype 2 and 3 (n = 180) |
|---|---|---|---|
| Female | 30 (42) | 37 (34) | 67 (37) |
| Age (years)a | 48 | 40 | 44 |
| BMI (kg/m2)a, b | 28 | 27 | 27 |
| log10 viral load (IU/L)a | 5.51 | 5.82 | 5.70 |
| METAVIR score | |||
| 0 | 5 (7) | 14 (13) | 19 (11) |
| 1 | 18 (25) | 26 (24) | 44 (24) |
| 2 | 27 (38) | 37 (34) | 64 (36) |
| 3 | 13 (18) | 19 (18) | 32 (18) |
| 4 | 9 (12) | 12 (11) | 21 (11) |
| Treatment duration | |||
| 24 weeks | 45 (62) | 81 (75) | 126 (70) |
| 48 weeks | 27 (38) | 27 (25) | 54 (30) |
| Early withdrawalc | 5 (7) | 7 (6) | 12 (7) |
| Late drop outd | 3 (4) | 9 (9) | 12 (7) |
Values in parentheses are percentages.
a
Mean.
b
One patient (genotype 2) did not have data of pretreatment BMI available.
c
These patients withdrew before week 12 either due to poor tolerance or adverse events.
d
These patients dropped out or did not submit blood sample for SVR assessment 24 weeks after completing therapy.