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. 2002 Dec;120(6):897–906. doi: 10.1085/jgp.20028608

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Copyright © 2002, The Rockefeller University Press

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Figure 5. — Effect of UTP on apical membrane Cl^- conductance. (A) Representative trace showing the transient change in apical membrane current after stimulation with 1 μM UTP using monolayers where the basolateral membrane was permeabilized with amphotericin B (10 μM). The basolateral membrane was bathed with KMeSO₄ saline solution, while the apical membrane was bathed with standard porcine saline solution. (B) Current-voltage relationship showing the UTP-activated current obtained in response to voltage steps from −90 to 90 mV in 15-mV increments from a holding potential of 0 mV.