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. 2002 Dec;120(6):855–873. doi: 10.1085/jgp.20028676

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Copyright © 2002, The Rockefeller University Press

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Figure 4. — Intraburst closed times are scarcely voltage dependent. (A) Frequency distributions of intraburst closed times at two exemplary membrane potentials (−40 mV in A1, −20 mV in A2). The histograms have been constructed pooling together data from seven (−40) or nine (−20) different patches. Data are shown binned linearly and plotted on a double-linear scale (bin width = 0.1 ms). Smooth lines are the best second-order exponential fittings obtained applying Eq. 1 to log-log plots of the same data binned logarithmically (see the materials and methods, and Fig. 2). Fitting parameters are specified in Table I. For both test potentials, exemplary 100-ms current-trace segments were selected from 500-ms sweeps recorded in a single representative patch (patch D8716), and are shown in the inset of the corresponding panel over an expanded time scale (calibration bars: 1 pA, 10 ms). (B) Plot of mean intraburst closed time (, calculated from fitting parameters as explained in the text) as a function of membrane potential.

Inline graphic — Intraburst closed times are scarcely voltage dependent. (A) Frequency distributions of intraburst closed times at two exemplary membrane potentials (−40 mV in A1, −20 mV in A2). The histograms have been constructed pooling together data from seven (−40) or nine (−20) different patches. Data are shown binned linearly and plotted on a double-linear scale (bin width = 0.1 ms). Smooth lines are the best second-order exponential fittings obtained applying Eq. 1 to log-log plots of the same data binned logarithmically (see the materials and methods, and Fig. 2). Fitting parameters are specified in Table I. For both test potentials, exemplary 100-ms current-trace segments were selected from 500-ms sweeps recorded in a single representative patch (patch D8716), and are shown in the inset of the corresponding panel over an expanded time scale (calibration bars: 1 pA, 10 ms). (B) Plot of mean intraburst closed time (, calculated from fitting parameters as explained in the text) as a function of membrane potential.