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. 2003 Nov;122(5):521–539. doi: 10.1085/jgp.200308885

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Copyright © 2003, The Rockefeller University Press

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Figure 6. — αD97H does not affect desensitization. (A) Low time-resolution view of currents elicited by 100 μM ACh. Below, higher time-resolution view of boxed clusters. (B) Dwell time histograms that pertain to all intervals in the record. The fastest closed-interval component reflects activation and the remaining four components reflect desensitization. (C) The desensitization rate constants were similar to those estimated for wt AChRs (Elenes and Auerbach, 2002; see Table V).