Examples of phyletic pattern search. (A) COGs represented in Encephalitozoon cuniculi but missing in the two yeasts (B) COGs represented in Yersinia pestis but not in other Proteobacteria or eukaryotesThe sets of species included in COGs are color-coded as follows (from left to right): yellow, archaea; purple, eukaryotes; green, miscellaneous bacteria, including hyperthermophiles, cyanobacteria, Fusobacterium, and Deinococcus; dark yellow, actinobacteria; torqoise, low-GC Gram-positive bacteria (except for mycoplasmas); light blue, Gamma-proteobacteria; dark-blue, Beta- and Epsilon-proteobacteria; dark gray, Alpha-proteobacteria; green, chlamydia and spirochetes; dark green, mycoplasmas. The functional categories, designated as in Fig. 4, are also color-coded.