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. 2003 Dec;122(6):749–760. doi: 10.1085/jgp.200308823

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Copyright © 2003, The Rockefeller University Press

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Figure 10. — PsTx inhibition of CNGA2 is not state dependent. Currents were recorded from outside-out patches excised from oocytes expressing CNGA2. Patch electrodes were filled with control solution containing either 1 mM cGMP or 2 μM cGMP as indicated. Traces represent currents measured in 10 mM MgCl₂ (top), 20 nM PsTx (middle), and control solution (bottom). In the rightmost panel, the patch current elicited in 2 μM cGMP was scaled to that of the 1 mM to facilitate comparison of PsTx block. Bars: 1 nA and 50 ms.